Neurological Disorders: Public Health Challenges

Pharmacological treatment for neurological disorders has increased these days, despite aggressive research, patients suffering from fatal or debilitating central nervous system (CNS) diseases, such as brain tumors, HIV encephalopathy, epilepsy, cerebrovascular diseases and neurodegenerative disorders, far outnumber those dying of all types of systemic cancers or heart diseases. Neurological disorders are frequently encountered in clinical practice. They have a poor prognosis and treatment options are limited. Their etiology is unknown, but leading theories propose a disturbance of somatic self-representation: the mind perceives dysfunction of a body region despite intact motor and sensory pathways. Central to this model is the concept of an abnormal top-down cognitive influence upon sensorimotor function. There is growing interest in the use of 5-HT2A agonists in the management of neuropsychiatric conditions. Recent studies have shown that these agents induce changes in neural activity that disrupt hierarchical brain dynamics and modulate networks sub-serving self-related processing. Converging evidence suggests they may hold unique therapeutic potential in functional neurological disorders. This is of importance given the considerable personal and societal burden of this condition and we argue a clinical trial to test this hypothesis is warranted. Neuroprotection strategies for ocular disorders require adequate behavioral readouts. In a clinical context, visual function is the sole determinant of successful therapy; however, many pre-clinical studies solely focus on molecular or cellular readouts to determine the effects of novel drug candidates.







About Aquilus International

Aquilus International promotes, support and facilitate the development of scientific research to understand and harness the potentiality of research innovations.

Know More
Latest Updates
  • Neuro and Infectious or non-infectious diseases
  • Complaints in Neurological disorder
  • Neurological Syndromes and Parasites
  • Neurological Disorders Epidemiology
  • Nonorganic Neurologic Disorders
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
  • Neurological Disorders
  • Neurologic Complications
  • Neuro diseases
  • Nonorganic Neurologic Disorders
  • Disease modeling
  • Neurogenic bladder
  • Rheumatoid Arthritis
  • Neurological services
  • Movement disorders
  • Neonatal encephalopathy
  • Brain concussion
Know More
Contact Us
  • Plot No. 754, DBK Heights
    4th Floor Ayyappa society
    Madhapur, Hyderabad - 81,  
    Telangana, India - 500081.

  • Phone Number - +91 40 6999 6909

    +91 40 4646 4575

  • Fax Number - +91 40 4646 4890